World pharmaceutical sales by region forecast 2027

Total pharmaceutical sales numbers in North America are projected to amount to some 992 billion U.S. dollars in 2027, making it the regional submarket with the highest global pharma sales by far.

Pharmaceutical spending and product revenue

In 2027, the United States is projected to spend between 685 and 715 billion U.S. dollars on medicine, making it the country with the highest pharmaceutical spending by far. China, which is estimated to be in second place, has a maximum projected expenditure estimate of 190 billion U.S. dollars for that year. The top pharmaceutical products for 2026 are expected to be Keytruda, Opdivo, and Eliquis, respectively. Keytruda by Merck & Co is forecast to generate almost 27 billion U.S. dollars in revenue in 2026.

Chemical and biological substances

Given that U.S. pharmaceutical R&D expenditures are the highest in the world, it comes to no surprise that the United States produces the largest volume of new chemical or biological entities each year. Between 2018 and 2022, American companies introduced a total of 159 new chemical or biological substances. Within the same period, Europe introduced 74 new entities.